Author: Nguyen Van Nguyen, Huynh Van Ba
ABSTRACT
Acne is inflammation of sebacous hair follicles. Acne pathogenesis is commonly related to endogenous and exogenous factors, but clearly related to 4 factors: increased production of sebum, folliculitis keratosis neck glands, bacterial activities in which the main role is propionibacterium acnes and inflammation. If treated promptly with correct methods, the disease is usually kept in good condition without any serious consequences and does not affect much to life quality of people. In fact, when having acnes, people usually treat them themselves in many different ways. In particular, self-treatment is the problem that is very common. On the other hand, overusing of antibiotics may be the cause of drug resistance of acne bacteria or overusing of topical medications that contain corticosteroids in self-treatment.
Objective:
- Identify the prevalence of p.acnes distributed according to the characteristics of patients with acnes examined in Can Tho Hospital of Dermatology.
- Identify the rate of resistance to antibiotics of p.acnes distributed according to characteristics of the patients examined in Can Tho Hospital of Dermatology.
Method: Descriptive cross-sectional with analysis
Result: The study of 100 patients examined and treated in Can Tho Hospital of Dermatology was noted as follows:
- acnes rate isolated from the patients: 39% of cases isolated with P.acnes. In particular, common acne (13%), cystic acne nodules (4%) and mostly acne pustules (17%), moderate (17%), severe (13%), patients with sensitive skin conditions (59%).
- Resistance rate of P.acnes to antibiotics Tetracylin (100%), Levofloxacin (66,7%), Erythromycin (92,3%), Trimethoprim/ Sulfamethoxazol (94,9%), Cefuroxim(53,8%). In particular, the rate of antibiotic sensitivity was 30,8% for Cefuroxime and 25,6% for Levofloxacin. Particularly, the resistance rate of p. acnes to both antibiotics was 15,4%, the resistance rate ≥ 3 diffenrent antibiotics largely accounted for 84,6%.
Conclusion:. Althought a number of antibiotics had been included in the treatment regimen, but resistance rate to antibiotics was still very high, Tetracyline (100%), Trimethoprim/ Sulfamethoxazol (94,9%).
Key words: Propionibacterium Acnes, Resistance.