Assoc. Prof. HUYNH VAN BA PhD.,MD
Head of Department of Dermato-Venereology
Can Tho University of medicine and pharmacy
Vice President, Vietnamese Society of Dermatology and Venereology
ABSTRACT
Herpes zoster is a common skin disease caused by virus so that it has a special affinity with skin and nerves. Pathogen is Varicella zoster virus, with clinical manifestations are characterized by lesions that grow in clusters on erythema and arrange on skin with nervous innervation, with the feature that lesions locate in one side of the body.
Objective
Identify the rate and a number of factors related to bacterial superinfection in patients treated in Can Tho Hospital of Dermato- venereology.
Identify the resistance rate of bacterial superinfection to antibiotics in patients with Herpes Zoster.
Method:Descriptive cross-sectional analysis
Result
The study of 48 inpatients with Shingles treated in Can Tho Hospital of Dermato-venereology from April of 2014 to September of 2015, the result was recored as follows:
The rate of bacterial superinfection was 21/48 (43,75%). In particular, the rate of infection by Staphyloccocus aureus was highest with 25% and Streptococcus with 25%.
A number of factors related to the reality of bacterial superinfection: bacterial superinfection was less likely to happen with patients who came to hospital 3 days later. Bacterial superinfection was more likely to happen with patients treated by themselves by the faulty method in the folk before reaching the hospital. Hospitalization ≥ 1 week was predominant (21%) with bacterial superinfection.
The resistance rate of Staphylococcus aureus to antibiotics: Antibiotics with high sensitivity rate: Vancomycin (100%), Ciprofloxacin (76,9%), Linezolid (100%), Amikacin (85,7%). Antibiotics with high resistance rate: Penicillin G (100%), Colistin (100%), Ceftazidim (100%), Amoxcillin/Clavulanic (100%), Erythromycin (73,3%), Trimethoprim/Sulfamethoxazol (83,3%), Tetracyclin (88,9%).
Conclusion: The infection rate of Staphyloccocus aureus was highest 25%, the rate of bacterial superinfection was high in patients treated with the faulty method in the folk before reaching hospital. Antibiotic with high sensitivity rate: Vancomycin (100%) and antibiotics with high resistance rate: Penicillin G (100%), Colistin (100%), Ceftazidim (100%), Amoxcillin/Clavulanic (100%). It was necessary to pay attention to the use of antibiotics in treatment of Shingles, especially with patients reaching hospital after 3 days, self-treating without any doctor’s indications or using faultymethod in the fold before reaching hospital.
Key words: Herpes zoster, bacterial superinfection
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